What Inspired One Woman to Drop a Staggering 530 Pounds?
( 03:53 )
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VIDEO DESCRIPTION:

It's the most astonishing weight loss story in the history of 'The Oprah Winfrey Show.' Nancy Makin, tipping the scales at 703 pounds, was too big to drive a car and, for more than 12 years, rarely left her apartment. She later heard that neighbors had taken to calling her 'the monster down the hall.' Watch as Nancy shares how she reversed course from a path that was leading her to an early death. (Original airdate: November 28, 2007)

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